Others include agents used to fight cancer or suppress the immune system in people who have received an organ transplant. Many of the drugs are common, such as some cholesterol-lowering statins, antibiotics and calcium channel blockers used to treat high blood pressure. Taking one tablet of some medications with a glass of grapefruit juice can be like taking 20 tablets, says David Bailey. "Between 20, the number of drugs in the list has gone from 17 to now 44." "What I've noticed over the last four years is really quite a disturbing trend, and that is the increase in the number of drugs that can produce not only adverse reactions but extraordinarily serious adverse drug reactions," Bailey said. Grapefruit juice is known to interact with some types of medications, leading to an overdose hazard.īailey reviews new product monographs and prescribing information for the Canadian Pharmacists Association, and keeps a close eye on those with the potential to produce serious adverse reactions. Since then, he said, the number of drugs with the potential to interact has jumped to more than 85. More prescription drugs are on the market that can interact with grapefruit juice with potentially serious effects including sudden death, Canadian doctors warn.ĭavid Bailey, a clinical pharmacologist at the Lawson Health Research Institute in London, Ont., discovered the interaction between grapefruit and certain medications more than 20 years ago.
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